About Rose Hips
GRAS food ingredient. Active compound is GOPO, a galactolipid with anti-inflammatory and cartilage-protective properties. Meta-analysis of 3 RCTs (n=287) showed small-to-moderate pain reduction in OA (ES 0.37, NNT=6), but all trials were manufacturer-funded (Hyben Vital). No independent replication. Vitamin C content is negligible after drying — clinical benefits come from GOPO, polyphenols, and fatty acids. Shell-only products lack GOPO and show no effect. Safety profile is favorable up to 10.5g/day. No established RDA/UL.
What Rose Hips supports
- Supports joint comfort in osteoarthritis (meta-analysis: ES 0.37, NNT=6)
- GOPO galactolipid inhibits neutrophil chemotaxis and inflammatory pathways
- Provides polyphenol and carotenoid antioxidant support
How much Rose Hips to take
Clinical studies typically use 2500–5000 mg of Rose Hips. Standard OA dose is 5g/day (2.5g twice daily). Individuals under 84kg may respond at 2.25g/day. Effects take ~3 weeks to manifest. Must contain seeds + shells for GOPO galactolipid content.
- Effective range
- 2500–5000 mg
Clinical evidence
Limited clinical evidence. Meta-analysis of 3 small trials (287 participants) shows modest pain relief, all manufacturer-funded
Reference