BioStacks

Fatty Acid

Stearidonic Acid (SDA)

Evidence

Limited
Evidence: 2 of 5 (Limited)

What the evidence says

Stearidonic acid (18:4 n-3) is a plant-derived omega-3 (echium, hemp, some GM soybean oil) that bypasses the rate-limiting delta-6-desaturase step, so it raises EPA in blood more efficiently than ALA does, though far less than direct EPA/DHA.

Raises EPA better than ALA in trials; no standalone clinical-outcome evidence.

Top Stearidonic Acid (SDA) supplements

About Stearidonic Acid (SDA)

Stearidonic acid (18:4 n-3) is a plant-derived omega-3 (echium, hemp, some GM soybean oil) that bypasses the rate-limiting delta-6-desaturase step, so it raises EPA in blood more efficiently than ALA does, though far less than direct EPA/DHA. Human trials confirm EPA enrichment but do not establish independent clinical outcomes. Grades low: interesting as a more-convertible plant omega-3, but no standalone efficacy evidence and negligible DHA conversion.

What Stearidonic Acid (SDA) supports

  • Converts to EPA more efficiently than ALA, offering a plant omega-3 route, though conversion to DHA is negligible

How much Stearidonic Acid (SDA) to take

The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.

Effective

00

mg

No established therapeutic dose; positioned as a plant omega-3 intermediate. Nominal range for a fatty-acid-profile line item.

Clinical evidence

Limited clinical evidence. Raises EPA better than ALA in trials; no standalone clinical-outcome evidence.