BioStacks

Supplement

Dihydroquercetin

Evidence

Limited
Evidence: 2 of 5 (Limited)

What the evidence says

A flavanonol (the dihydro form of quercetin), typically sourced from larch. Strong antioxidant and anti-inflammatory activity in vitro and in animals; a handful of small human studies (e.g. in metabolic and hepatic conditions) exist but the body of randomized human evidence is very limited, and oral bioavailability is low (~24%).

Low: mostly mechanistic/preclinical; human RCT evidence sparse and doses unstandardized.

Top Dihydroquercetin supplements

About Dihydroquercetin

A flavanonol (the dihydro form of quercetin), typically sourced from larch. Strong antioxidant and anti-inflammatory activity in vitro and in animals; a handful of small human studies (e.g. in metabolic and hepatic conditions) exist but the body of randomized human evidence is very limited, and oral bioavailability is low (~24%). Its glycoside dihydroquercetin-3-rhamnoside is a related label variant. Grade low — mostly mechanistic/preclinical.

What Dihydroquercetin supports

  • Acts as a strong antioxidant in lab and animal studies
  • Preliminary human data in metabolic and vascular health (limited, early)

How much Dihydroquercetin to take

The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.

Effective

00

mg

No established therapeutic dose; human trials are sparse and doses are not standardized. Usually present as a minor flavonoid marker (often from Siberian larch or as a quercetin companion). Nominal placeholder range.

Clinical evidence

Limited clinical evidence. Low: mostly mechanistic/preclinical; human RCT evidence sparse and doses unstandardized.

NIH Fact Sheet