About Turkey Tail Mushroom
Turkey tail contains PSK (polysaccharide-K) and PSP (polysaccharopeptide), two protein-bound polysaccharides with strong immunomodulatory evidence. PSK is an approved adjunctive cancer therapy in Japan with multiple RCTs showing improved survival in gastric and colorectal cancer patients. A 2012 NIH-funded Phase I trial showed dose-dependent immune activation in breast cancer patients. Among the most clinically studied medicinal mushrooms. Generally well tolerated.
What Turkey Tail Mushroom supports
- Strong immune modulation via PSK and PSP polysaccharides
- Studied as adjunctive immunotherapy in oncology
- Prebiotic effects supporting gut microbiome diversity
How much Turkey Tail Mushroom to take
Clinical studies typically use 1000–3000 mg of Turkey Tail Mushroom. Studies use 1–3 g/day of extract. PSK (Krestin) dosed at 3 g/day in Japanese oncology trials.
- Effective range
- 1000–3000 mg
Clinical evidence
Moderate clinical evidence. Multiple clinical trials in Japan as adjunctive cancer therapy; PSK is a prescription immunotherapy there
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