**Nattokinase** at 4,000 FU per capsule — right at the top of the clinically studied range for cardiovascular support. A meta-analysis of six RCTs found this dose range can modestly reduce blood pressure and enhance your body's natural ability to break down fibrin, the protein involved in blood clot formation. The NSK-SD branded form used here is vitamin K-free, which matters if you're on blood thinners.

The formula also includes a blend of digestive enzymes alongside the nattokinase, though the **Bromelain** at 96 GDU is well below the 1,200+ GDU range studied for anti-inflammatory benefits — at this dose, it's contributing to digestion rather than joint or inflammation support.

The directions suggest taking this on an empty stomach, which is important — nattokinase's fibrinolytic activity is best studied when taken away from food. If you're using blood-thinning medication, check with your doctor before adding this to your routine.

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BioStacks

Enzyme Science

Nattokinase Pro

Capsule · 60 servings · $0.78/serving

49 / 100Average

Score Breakdown

Formulation
49
Safety
100
Final score
49/100

Ingredients (9)

7 scored · 2 not scored

Nattokinase4000 FU

Optimal dose

Cellulase1000 CU

Within effective range

Glucoamylase40 AGU

Within effective range

Lipase685 FIP

69% of effective dose

Protease16000 HUT

53% of effective dose

Label Nutrition Facts

Active Ingredients

From the label · % Daily Value

DV%

Nattokinase4000 FU

Calcium14 mg

1%

Magnesium0.04 mg

Bromelain96 GDU

Amylase3600 DU

Other Ingredients

Fillers, coatings, and additives

Vegetarian Capsule (Cellulose, Water)

Unknown

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.