**Nattokinase** at 4,000 FU per capsule — right at the top of the clinically studied range for cardiovascular support. A meta-analysis of six RCTs found this dose range can modestly reduce blood pressure and enhance your body's natural ability to break down fibrin, the protein involved in blood clot formation. The NSK-SD branded form used here is vitamin K-free, which matters if you're on blood thinners.

The formula also includes a blend of digestive enzymes alongside the nattokinase, though the **Bromelain** at 96 GDU is well below the 1,200+ GDU range studied for anti-inflammatory benefits — at this dose, it's contributing to digestion rather than joint or inflammation support.

The directions suggest taking this on an empty stomach, which is important — nattokinase's fibrinolytic activity is best studied when taken away from food. If you're using blood-thinning medication, check with your doctor before adding this to your routine.

BioStacks
Enzyme Science

Nattokinase Pro

1 Capsule · 60 servings · $0.78/serving

iHerbAmazon

Best for

Heart

Ingredients (9)

Nattokinase

100%

Dose

4000 FU

Target

2000–4000 fu

Form

—

Cellulase

100%

Dose

1000 CU

Target

500–1000 cu

Form

—

Glucoamylase

100%

Dose

40 AGU

Target

20–50 agu

Form

—

Lipase

69%

Dose

685 FIP

Target

1000–3000 fip

Form

—

Protease

53%

Dose

16000 HUT

Target

30000–60000 hut

Form

—

Other Ingredients (1)

Capsule ShellCapsule

Generic capsule shell where the label does not specify the material. Common materials are hypromellose (HPMC) for vegetarian capsules and gelatin for traditional capsules — both are GRAS-listed and safe. Fish gelatin and pullulan variants also exist.

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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