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Life Extension

Esophageal Guardian (Berry)

2 Tablets · 30 servings · $0.80/serving

iHerbAmazon

Every active here is dosed below the amount studied to work. See how each one compares in the breakdown below.

Best for

Heart

Ingredients (5)

Ellagic Acid

7%

Dose

35 mg

Target

500–1500 mg

Form

—

Strawberry extract

8%

Dose

416 mg

Target

5000–15000 mg

Form

—

Magnesium

40 mg

Trace amount — not scored

Calcium

80 mg

Trace amount — not scored

Alginic Acid

1000 mg

Not in our database

Other Ingredients (11)

MaltodextrinBinder

Spikes blood sugar faster than table sugar (glycemic index 85–105). Research links it to gut bacteria changes that may promote intestinal inflammation (Nickerson et al. 2015). Used as a cheap filler — adds nothing beneficial.

MannitolSweetener

A FODMAP sugar alcohol that can cause GI distress (bloating, gas, diarrhea) at higher doses. Supplement amounts are typically small, but individuals with IBS or sugar alcohol sensitivity may react even at low doses.

XylitolSweetener

A FODMAP sugar alcohol that can cause GI distress (bloating, gas, diarrhea) at moderate doses (>10-20g/day), though supplement amounts are typically small. Extremely toxic to dogs — households with pets should store securely.

Natural FlavorsFlavor

Broad regulatory category of flavor constituents derived from natural sources. Composition is proprietary and not disclosed — 'Natural Flavors' can include several hundred different compounds depending on the target flavor profile, including hexane-extracted constituents and proprietary carrier solvents. 'Natural' is a regulatory definition (21 CFR §101.22), not a safety guarantee.

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

Vegetable StearateLubricant

A plant-derived salt of stearic acid (typically magnesium or calcium) used as a tablet lubricant

Citric AcidAcidulant

Natural acid derived from citrus fruits

Croscarmellose SodiumDisintegrant

Cross-linked cellulose derivative used as a superdisintegrant

How to Take It

Take it anytime

Timing doesn't matter for this one — taking it consistently does.

With or without food

On the label

After the heaviest meal of the day, chew two (2) tablets followed by 4 to 8 oz. of water, or as recommended by a healthcare practitioner. Do not swallow tablets whole.

General guidance based on the ingredients, not a substitute for the label or your doctor.

Price Check

$24.00

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Near the median of 22 pomegranate supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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