BioStacksBest Citrulline for Muscle
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Clinical dose: 3000–6000 mg
Citrulline and muscle
Citrulline is a supporting nutrient for muscle support. L-Citrulline is a non-essential amino acid that converts to L-arginine in the kidneys, raising plasma arginine and nitric oxide levels more effectively than oral arginine supplementation (arginine undergoes significant first-pass metabolism). Well-tolerated with no established UL. Citrulline malate is the most common supplemental form.
How much citrulline do you need
Research points to 3000–6000 mg as the effective range for citrulline. 3-6g/day for NO-mediated blood flow and exercise performance. Citrulline malate studies often use 6-8g (which contains ~3-4.5g pure citrulline). Lower doses may provide some benefit, but most studies showing clear results used this range.
What the research says
The clinical evidence for citrulline in muscle is moderate. Several trials show it raises nitric oxide more effectively than oral arginine for blood flow Learn more