BioStacksBest Selenium for Longevity
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Clinical dose: 100–200 mcg
Why Selenium for Longevity
When it comes to longevity, Selenium is one of the most supporting nutrients to consider. Essential component of selenoproteins including glutathione peroxidase (antioxidant defense) and deiodinases (thyroid hormone activation). Selenomethionine is the most bioavailable supplemental form, while sodium selenite is inorganic and less efficiently absorbed. Brazil nuts are the richest food source—just 1–2 nuts can meet the daily requirement.
What dose to look for
Clinical studies typically use 100–200 mcg of selenium. Common supplement dose; UL is 400 mcg/day. Supplements that fall short of this threshold are unlikely to match what clinical trials achieved.
What form to look for
Avoid sodium selenite — inorganic, lower retention. For best results, choose selenomethionine.
The evidence behind selenium
Research supporting selenium for longevity is rated as strong. SELECT trial (35,000+ men) found no cancer prevention benefit; essential for thyroid via selenoproteins Learn more