Best Selenium for Longevity
Top 3 products ranked
Last reviewed May 2026
Clinical dose: 100–200 mcg
Why Selenium for Longevity
Selenium plays a supporting role in longevity. Essential component of selenoproteins including glutathione peroxidase (antioxidant defense) and deiodinases (thyroid hormone activation). Selenomethionine is the most bioavailable supplemental form, while sodium selenite is inorganic and less efficiently absorbed.
What dose to look for
Clinical studies typically use 100–200 mcg of selenium. Common supplement dose; UL is 400 mcg/day. Products below this range may not deliver meaningful results.
What form to look for
Avoid sodium selenite — inorganic, lower retention. Look for selenomethionine for better absorption.
What the research says
Selenium has strong clinical evidence for longevity benefits. SELECT trial (35,000+ men) found no cancer prevention benefit; essential for thyroid via selenoproteins Learn more
