About Adrenal cortex extract
Glandular tissue extract (usually bovine) marketed for 'adrenal fatigue'/stress. No RCTs support efficacy; 'adrenal fatigue' is not a recognized clinical diagnosis. Bovine-sourced glandulars carry theoretical prion/contamination concerns and possible unlabeled steroid content. Not scoreable against a therapeutic dose.
What Adrenal cortex extract supports
- Traditionally used for stress/energy support — no RCT confirmation of any benefit
Clinical evidence
Limited clinical evidence. No controlled human trials; use is based on tradition and marketing, not evidence.
NIH Fact Sheet