About Agmatine
A decarboxylation product of arginine marketed in pre-workouts for pumps and as a neuromodulator. Most evidence is from animal models (neuropathic pain, mood); controlled human trials for performance or mood are lacking.
What Agmatine supports
- Arginine metabolite marketed for pumps (weak evidence)
How much Agmatine to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
500–1000
mg
Pre-workout products use ~500-1,000 mg; human efficacy dosing not established.
Clinical evidence
Limited clinical evidence. Largely animal data; controlled human trials lacking
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