BioStacks

Supplement

Beta-Glucan

Evidence

Moderate
Evidence: 3 of 5 (Moderate)

What the evidence says

Multiple RCTs for upper respiratory infection reduction in healthy adults (Auinger et al. 2013, Fuller et al. 2012). Yeast-derived (1,3/1,6) form is most studied for immune function. Oat-derived beta-glucan has separate FDA health claim for cholesterol (different mechanism).

Multiple clinical trials show reduced upper respiratory infections in healthy adults

Top Beta-Glucan supplements for…

Top Beta-Glucan supplements

About Beta-Glucan

Multiple RCTs for upper respiratory infection reduction in healthy adults (Auinger et al. 2013, Fuller et al. 2012). Yeast-derived (1,3/1,6) form is most studied for immune function. Oat-derived beta-glucan has separate FDA health claim for cholesterol (different mechanism). Generally recognized as safe.

What Beta-Glucan supports

  • Reduces incidence and duration of upper respiratory infections (multiple RCTs)
  • Supports innate immune cell activity (NK cells, macrophages)

How much Beta-Glucan to take

The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.

Effective

250–500

mg

250–500 mg/day yeast-derived 1,3/1,6-beta-glucan. URI reduction trials used 250 mg/day (Auinger et al. 2013).

Clinical evidence

Moderate clinical evidence. Multiple clinical trials show reduced upper respiratory infections in healthy adults

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