About Bonito (fish) protein peptides / PeptACE
Bonito (fish) protein hydrolysate peptides act as mild ACE inhibitors in vitro. A small number of short, mostly manufacturer-associated human trials suggest modest blood-pressure effects in borderline-hypertensive subjects, but the evidence base is thin and not confirmed by independent large RCTs.
What Bonito (fish) protein peptides / PeptACE supports
- Small studies suggest modest blood-pressure support — evidence is limited and not independently confirmed
How much Bonito (fish) protein peptides / PeptACE to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
1000–1500
mg
Small human studies on bonito-derived ACE-inhibitory peptides used roughly 1.5g/day; branded PeptACE products are typically sold at ~500mg per capsule with multi-capsule servings.
Clinical evidence
Limited clinical evidence. Evidence limited to a small number of short trials; not confirmed by independent large RCTs.
NIH Fact Sheet