About Boswellia Serrata Extract
Boswellia serrata is a resin extract with strong anti-inflammatory evidence via 5-lipoxygenase inhibition. A 2020 meta-analysis (7 trials, 545 OA patients) found significant pain and stiffness relief. A 2025 network meta-analysis (20 RCTs, 1,633 participants) confirmed WOMAC improvements. Efficacy depends heavily on boswellic acid and AKBA standardization — enriched extracts (Aflapin, 5-Loxin) are effective at lower doses than standard extracts.
What Boswellia Serrata Extract supports
- Reduces joint pain and stiffness in osteoarthritis (multiple meta-analyses, 20+ RCTs)
- Anti-inflammatory via 5-lipoxygenase inhibition
How much Boswellia Serrata Extract to take
Clinical studies typically use 300–1200 mg of Boswellia Serrata Extract. Dose depends on AKBA standardization. Standard extract (30–40% boswellic acids): 900–1200 mg/day. Enriched AKBA extracts like 5-Loxin (30% AKBA): 100–250 mg/day. Aflapin (20% AKBA): 100 mg/day. Safe up to 1000 mg/day for 6 months.
- Effective range
- 300–1200 mg
Clinical evidence
Moderate clinical evidence. Meta-analyses of 20+ trials (1,633 participants) confirm joint pain and stiffness relief
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