About DMF (from Kaempferia parviflora)
5,7-Dimethoxyflavone is a flavone found in Kaempferia parviflora ('Thai black ginger') and other plants, marketed for testosterone/performance support. Evidence is limited to cell and animal studies (anti-obesity, anti-diabetic, anti-sarcopenia effects in aged mice); no human clinical trials were identified. It inhibited CYP3A liver enzymes in an animal drug-interaction study (increasing midazolam exposure), a plausible interaction concern that has not been characterized in humans.
What DMF (from Kaempferia parviflora) supports
- Marketed for testosterone/performance support — evidence is limited to animal and cell studies, no human trials
Clinical evidence
Limited clinical evidence. No human trials; animal/mechanistic evidence only. Possible CYP3A drug interaction flagged in animal data, unconfirmed in humans.
NIH Fact Sheet