About L-Ergothioneine (ErgoActive)
Ergothioneine is a naturally occurring antioxidant amino acid found in mushrooms, marketed as a 'longevity' ingredient (branded ErgoActive by Blue California, produced via fermentation). Early small randomized, placebo-controlled human trials suggest possible cognitive and skin benefits, but the evidence base is preliminary and mostly funded/associated with the ingredient manufacturer.
What L-Ergothioneine (ErgoActive) supports
- Early small RCTs suggest cognitive/skin antioxidant benefits — evidence is preliminary and mostly manufacturer-associated
How much L-Ergothioneine (ErgoActive) to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
5–25
mg
Recent small RCTs on cognitive/skin endpoints have used doses in roughly this range; larger confirmatory trials are limited.
Clinical evidence
Limited clinical evidence. Preliminary small RCTs only; independent large-scale confirmation is lacking.
NIH Fact Sheet