Eriocitrin

A flavanone glycoside abundant in lemons and limes. One industry-funded RCT (Ribeiro 2019, n=103 prediabetics) using Eriomin branded extract showed improvements in fasting glucose, insulin resistance, HbA1c, and inflammatory markers (hsCRP, IL-6, TNF-α) over 12 weeks. A second smaller crossover trial confirmed effects via GLP-1 increase. Antioxidant activity demonstrated in vitro. Bioavailability of the parent compound is low, but gut microbiota hydrolyze it to eriodictyol, which is better absorbed. No independent replication outside the Eriomin research group.