About Aframomum melegueta Seed Extract
Several small, mostly industry-funded human RCTs show Grains of Paradise (standardized to 6-paradol) activates brown adipose tissue and increases energy expenditure. Effects on actual body-fat/weight loss are modest and not yet confirmed by independent, larger, or meta-analytic evidence.
What Aframomum melegueta Seed Extract supports
- Small human trials show increased brown-fat activity and energy expenditure — effect on actual body fat is modest and not independently confirmed
How much Aframomum melegueta Seed Extract to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
30–500
mg
Human RCTs range from 40 mg/day (brown-fat activation) to 250 mg twice daily / 500mg standardized extract (visceral fat/energy expenditure).
Clinical evidence
Limited clinical evidence. Multiple small RCTs (mostly industry-funded) on energy expenditure; no meta-analysis and modest real-world fat-loss effect.
NIH Fact Sheet