BioStacks

Herb

Soursop Leaf

Evidence

Limited
Evidence: 2 of 5 (Limited)

What the evidence says

Leaf extract of Annona muricata (soursop), heavily marketed for anticancer effects based only on in-vitro/animal data — there are no human RCTs supporting anticancer or other therapeutic claims. Important safety flag: long-term consumption has been linked in observational studies to atypical Parkinsonism, likely due to the neurotoxic compound annonacin.

Only in-vitro/animal data for efficacy claims; safety signal (neurotoxicity/annonacin) is from observational human data.

Top Soursop Leaf supplements

About Soursop Leaf

Leaf extract of Annona muricata (soursop), heavily marketed for anticancer effects based only on in-vitro/animal data — there are no human RCTs supporting anticancer or other therapeutic claims. Important safety flag: long-term consumption has been linked in observational studies to atypical Parkinsonism, likely due to the neurotoxic compound annonacin. BioStacks does not endorse anticancer marketing claims for this ingredient.

What Soursop Leaf supports

  • No human clinical evidence supports anticancer or other health claims; long-term use linked to neurotoxicity concerns in observational studies

Clinical evidence

Limited clinical evidence. Only in-vitro/animal data for efficacy claims; safety signal (neurotoxicity/annonacin) is from observational human data.

Reference