About Horse Chestnut
Horse chestnut seed extract (standardized to aescin) for chronic venous insufficiency. A Cochrane review concluded it reduces leg pain, edema and itching in CVI, making it one of the better-supported venous botanicals. Raw seeds are toxic; only standardized extract is safe.
What Horse Chestnut supports
- Cochrane-supported for chronic venous insufficiency
How much Horse Chestnut to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
300–600
mg
Trials used extract standardized to ~50-150 mg aescin/day (≈300-600 mg extract).
Clinical evidence
Moderate clinical evidence. Cochrane review supports symptom relief in chronic venous insufficiency
Examine.com