About MSM
MSM is an organic sulfur compound found naturally in foods. Sulfur is essential for the formation of connective tissue, including cartilage, tendons, and ligaments. MSM has demonstrated anti-inflammatory and antioxidant properties in clinical studies. OptiMSM (by Bergstrom Nutrition) is the gold standard branded form, purified by distillation rather than crystallization. Generally very well tolerated even at higher doses. No established RDA/UL.
What MSM supports
- Provides bioavailable sulfur for cartilage and connective tissue
- Supports healthy inflammatory response, especially post-exercise
- May reduce exercise-induced muscle soreness and speed recovery
- Sulfur supports keratin production for hair, skin, and nail health
How much MSM to take
Clinical studies typically use 1000–3000 mg of MSM. Most studies use 1000–3000 mg/day. OptiMSM is the most clinically studied branded form, purified via distillation. Doses up to 6000 mg/day have been used in clinical trials without significant adverse effects.
- Effective range
- 1000–3000 mg
Clinical evidence
Moderate clinical evidence. Several clinical trials on joint comfort and inflammation, but most are small to moderate in size
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