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NAC

Amino Acid
NAC
Moderate Evidence

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About NAC

NAC is a precursor to glutathione, the body's primary intracellular antioxidant. Supports liver detoxification, respiratory health, and cellular defense against oxidative stress. Well studied for acetaminophen toxicity and as a mucolytic. Generally well tolerated; may cause GI discomfort at higher doses. No established RDA/UL.

What NAC supports

  • Supports glutathione production, the body's master antioxidant
  • Supports liver detoxification and cellular protection
  • Supports respiratory health and mucus clearance
  • May support healthy aging through oxidative stress defense

How much NAC to take

Clinical studies typically use 600–1800 mg of NAC. Most studies use 600–1200 mg/day. Higher doses (up to 1800 mg) used in some clinical contexts. Often taken in divided doses.

Effective range
600–1800 mg

Clinical evidence

Moderate clinical evidence. Precursor to glutathione with established medical use for acetaminophen toxicity and mucolytic therapy

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