About Nicotinamide Adenine Dinucleotide
The reduced form of NAD+, a coenzyme central to mitochondrial energy production. Small trials in chronic fatigue syndrome and jet lag suggest modest benefit, but oral bioavailability of intact NADH is questionable and evidence is weak.
What Nicotinamide Adenine Dinucleotide supports
- Coenzyme involved in mitochondrial energy production
How much Nicotinamide Adenine Dinucleotide to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
5–20
mg
Fatigue and cognition trials used 5-20 mg/day of stabilized oral NADH.
Clinical evidence
Limited clinical evidence. Small fatigue trials; oral bioavailability and benefit uncertain
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