About Pancreatin
Porcine pancreatic enzyme concentrate containing lipase, protease and amylase. Activity is graded in USP units relative to a standard (1X, 4X, 8X). Strong evidence for prescription-strength PERT in pancreatic insufficiency; limited data for low-dose OTC digestive supplements in healthy adults.
What Pancreatin supports
- Supports digestion of fats, proteins and carbohydrates
How much Pancreatin to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
100–500
mg
Pancreatin is a porcine multi-enzyme concentrate (lipase/protease/amylase) graded by activity strength (e.g. 4X, 8X USP), not mg. Strong evidence exists for prescription PERT in pancreatic insufficiency; OTC supplement doses are weakly supported. mg range is nominal for resolution.
Clinical evidence
Limited clinical evidence. Strong evidence for prescription PERT; limited data for OTC supplement doses
NIH Fact Sheet