About Phellodendron
Traditional Chinese medicine bark, a source of berberine and related alkaloids. Most human data come from proprietary combinations (magnolia + phellodendron) for stress/cortisol and weight, not phellodendron alone. Monotherapy clinical evidence is minimal.
What Phellodendron supports
- Studied mostly in combination formulas for stress and cortisol, with limited standalone evidence
How much Phellodendron to take
The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.
Effective
250–750
mg
Doses reflect standardized bark extract used in stress/cortisol combination products (e.g. paired with magnolia). No monotherapy therapeutic dose is well established; range is nominal.
Clinical evidence
Limited clinical evidence. Mostly blend-based human data; little evidence for phellodendron alone.