BioStacks

Supplement

Phytosterols

Evidence

Strong
Evidence: 4 of 5 (Strong)

What the evidence says

Plant sterols and stanols are among the few supplements with an FDA-authorized health claim: 800+ mg/day may reduce LDL cholesterol by 6-15%. Multiple meta-analyses confirm dose-dependent LDL reduction with diminishing returns above 3g/day.

FDA-authorized health claim; multiple meta-analyses confirm 6-15% LDL reduction at 2-3 g/day

Top Phytosterols supplements

About Phytosterols

Plant sterols and stanols are among the few supplements with an FDA-authorized health claim: 800+ mg/day may reduce LDL cholesterol by 6-15%. Multiple meta-analyses confirm dose-dependent LDL reduction with diminishing returns above 3g/day. Work by competing with cholesterol for intestinal absorption. May reduce absorption of fat-soluble vitamins (A, D, E, K) at high doses. No established RDA/UL.

What Phytosterols supports

  • Reduces LDL cholesterol absorption (FDA-authorized claim)
  • Supports cardiovascular health

How much Phytosterols to take

The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.

Effective

8003000

mg

FDA-authorized health claim at 800+ mg/day for cholesterol reduction; optimal at 2-3 g/day.

Clinical evidence

Strong clinical evidence. FDA-authorized health claim; multiple meta-analyses confirm 6-15% LDL reduction at 2-3 g/day

Examine.com