Phytosterols

Plant sterols and stanols are among the few supplements with an FDA-authorized health claim: 800+ mg/day may reduce LDL cholesterol by 6-15%. Multiple meta-analyses confirm dose-dependent LDL reduction with diminishing returns above 3g/day. Work by competing with cholesterol for intestinal absorption. May reduce absorption of fat-soluble vitamins (A, D, E, K) at high doses. No established RDA/UL.