BioStacks

Herb

Pycnogenol

Evidence

Moderate
Evidence: 3 of 5 (Moderate)

What the evidence says

Pycnogenol is a standardized extract from French maritime pine bark, rich in procyanidins. Over 100 published clinical studies. RCTs support benefits for venous insufficiency, skin photoprotection and elasticity, ADHD symptoms in children, and blood glucose management.

100+ clinical studies; strong RCT evidence for venous insufficiency, skin health, and glycemic control

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About Pycnogenol

Pycnogenol is a standardized extract from French maritime pine bark, rich in procyanidins. Over 100 published clinical studies. RCTs support benefits for venous insufficiency, skin photoprotection and elasticity, ADHD symptoms in children, and blood glucose management. The procyanidin content provides potent antioxidant and anti-inflammatory activity. Generally well tolerated. No established RDA/UL.

What Pycnogenol supports

  • Supports skin elasticity and UV protection
  • May improve venous circulation
  • May support blood glucose management

How much Pycnogenol to take

The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.

Effective

50200

mg

Standardized extract (65-75% procyanidins); 50-200 mg/day across clinical trials.

Clinical evidence

Moderate clinical evidence. 100+ clinical studies; strong RCT evidence for venous insufficiency, skin health, and glycemic control

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