BioStacks
Thymosin Beta-4 Fragment
Amino AcidLimited Evidence
Dosing Guide
RDA
None
Effective
2–10 mg
Upper Limit
None
Supplement doses range 2–10 mg/day. No human RCTs establish a therapeutic oral dose. Animal studies use injection. Oral bioavailability is uncharacterized.
About Thymosin Beta-4 Fragment
A synthetic fragment of thymosin beta-4, a naturally occurring protein involved in cell migration, wound healing, and angiogenesis. Animal injection studies show tissue repair and anti-inflammatory effects. Zero human RCTs for oral supplementation. TB-500 is banned by WADA as a prohibited growth factor. The intact peptide is a 43-amino acid chain almost certainly degraded by GI proteases before absorption. Regulatory status is gray-area — sold as a 'research chemical.'
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