BioStacks

Supplement

Uridine

Evidence

Limited
Evidence: 2 of 5 (Limited)

What the evidence says

A pyrimidine nucleoside involved in phospholipid and neuronal membrane synthesis. Promoted as a nootropic, often combined with DHA and choline; human evidence for cognition from uridine alone is limited and largely mechanistic or from combination formulas.

Mechanistic and combination-formula data; little standalone RCT support.

Top Uridine supplements

About Uridine

A pyrimidine nucleoside involved in phospholipid and neuronal membrane synthesis. Promoted as a nootropic, often combined with DHA and choline; human evidence for cognition from uridine alone is limited and largely mechanistic or from combination formulas.

What Uridine supports

  • Involved in brain-cell membrane synthesis; standalone cognitive evidence is limited

How much Uridine to take

The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.

Effective

2501000

mg

Nootropic use suggests ~250-1000 mg/day of uridine monophosphate, but this is extrapolated from small studies and combination products rather than robust monotherapy trials.

Clinical evidence

Limited clinical evidence. Mechanistic and combination-formula data; little standalone RCT support.