BioStacks

Herb

Ashwagandha Withanolides

Evidence

Moderate
Evidence: 3 of 5 (Moderate)

What the evidence says

The steroidal lactones responsible for much of ashwagandha's activity, listed on some labels as a standardized marker rather than total extract weight. Evidence tracks the ashwagandha entry (stress/cortisol, sleep).

Standardized active fraction of ashwagandha; see ashwagandha for trials

Top Ashwagandha Withanolides supplements

About Ashwagandha Withanolides

The steroidal lactones responsible for much of ashwagandha's activity, listed on some labels as a standardized marker rather than total extract weight. Evidence tracks the ashwagandha entry (stress/cortisol, sleep). Listed standalone so withanolide-marker rows resolve without misapplying the whole-extract dose range.

What Ashwagandha Withanolides supports

  • Active marker compounds of ashwagandha

How much Ashwagandha Withanolides to take

The RDA prevents deficiency. The effective range is what clinical trials used to actually move the outcome.

Effective

550

mg

Withanolides are the standardized active marker of ashwagandha; clinical extracts deliver roughly 5-50 mg of withanolides (e.g. KSM-66 ~5%, Sensoril ~10%). Scored separately here because withanolide mg is ~10-20x smaller than whole-extract mg.

Clinical evidence

Moderate clinical evidence. Standardized active fraction of ashwagandha; see ashwagandha for trials

Examine.com