C 500 mg

IARC classifies cosmetic-grade talc not containing asbestos as Group 2B (possibly carcinogenic to humans); perineal talc use as Group 2A (probably carcinogenic). Johnson & Johnson voluntarily withdrew talc-based baby powder from US/Canada in 2020 and globally in 2022 after extensive litigation tied to ovarian-cancer and mesothelioma cases. The 2018 FDA contamination survey found asbestos in 9 of 52 cosmetic talc products tested. As a supplement excipient talc is a pure manufacturing convenience — no nutritional or functional benefit to the user — so the asbestos-exposure risk has no offsetting upside. Safer alternatives (silicon dioxide, microcrystalline cellulose, rice hulls) are widely available.

Banned in the EU (2022) over concerns that its ultra-fine particles may damage DNA in gut cells. Still allowed in the US. Used only for white coloring — provides no health benefit.

A salt of stearic acid used as a lubricant in tablet and capsule production

Synthetic, water-soluble polymer used as a film former and binder in immediate-release tablet coatings

Fine silica powder used to prevent clumping

Plant-derived cellulose used as a binder and filler in supplements

Cross-linked cellulose derivative used as a superdisintegrant

Plant-derived capsule material from cellulose