BioStacks
21st Century

Niacin Inositol Hexanicotinate 500 mg

1 Capsule · 110 servings · $0.12/serving

29 / 100Poor

Best for

Score Breakdown

Formulation
39
Safety
75
Final score
29/100

Ingredients (2)

Niacin

100%

Dose

400 mg

Target

25–500 mg

Form

Budget

Inositol

5%

Dose

100 mg

Target

2000–4000 mg

Form

Budget

Other Ingredients (5)

TalcAnti-caking

IARC classifies cosmetic-grade talc not containing asbestos as Group 2B (possibly carcinogenic to humans); perineal talc use as Group 2A (probably carcinogenic). Johnson & Johnson voluntarily withdrew talc-based baby powder from US/Canada in 2020 and globally in 2022 after extensive litigation tied to ovarian-cancer and mesothelioma cases. The 2018 FDA contamination survey found asbestos in 9 of 52 cosmetic talc products tested. As a supplement excipient talc is a pure manufacturing convenience — no nutritional or functional benefit to the user — so the asbestos-exposure risk has no offsetting upside. Safer alternatives (silicon dioxide, microcrystalline cellulose, rice hulls) are widely available.

Magnesium StearateLubricant

A salt of stearic acid used as a lubricant in tablet and capsule production

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

GelatinCapsule

Protein derived from collagen, used in traditional capsule shells

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.