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Advanced Research

Zinc Orotate

1 Tablet · 200 servings · $0.08/serving

iHerbAmazon

Best for

Immune

Ingredients (1)

Zinc

100%

Dose

60 mg

Target

15–30 mg

Form

Budget

Other Ingredients (7)

CarboxymethylcelluloseThickener

Carboxymethylcellulose was the second emulsifier (with polysorbate 80) in Chassaing et al. 2015 (Nature, PMID 25731162), which showed mucus-barrier thinning, a microbiota shift toward pro-inflammatory species, low-grade inflammation, and metabolic syndrome in mice. Chassaing 2022 (Gastroenterology, PMID 34774538) tested CMC directly in a randomized controlled human feeding trial and found reduced microbial diversity and bacterial encroachment into the normally sterile mucus layer in a susceptible subset of participants. EFSA's 2018 re-evaluation could not establish a safe level due to data gaps. For a purely textural excipient, the gut-barrier risk profile is unfavorable when safer thickeners are widely available.

Magnesium Carbonate (excipient)Anticaking Agent

Magnesium carbonate used as an anti-caking, flow, and drying agent.

Glyceryl BehenateLubricant

Glyceryl ester of behenic acid used as a tablet lubricant and controlled-release matrix agent

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

Natural Palm Leaf GlazeCoating

A plant wax from the carnauba palm leaf used as a tablet glaze and polish

PolyvinylpyrrolidoneBinder

A synthetic polymer used as a tablet binder and film former

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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