Animal Juiced Aminos Grape Juiced

May trigger hyperactivity in sensitive children; potential link to allergic reactions

Same petroleum-derived azo dye as Red 40, linked to hyperactivity in children (Southampton study) and carrying an EU warning label; pure cosmetic color with zero benefit.

Dose context matters. As a trace excipient in a tablet coating or capsule, the amount is minimal and not a meaningful concern. The evidence below applies to the gram-level intakes typical of sweetened protein powders, pre-workouts, and drink mixes: a 2022 human trial (Suez et al., Cell) showed sucralose disrupts gut bacteria and worsens blood sugar control in healthy adults, and a 2023 study (Schiffman et al.) found that sucralose-6-acetate — a compound formed when sucralose is digested — was genotoxic to human cells in vitro. It remains an artificial sweetener with no nutritional purpose.

Older NTP rodent studies (1980s, contested) reported lymphoma and leukemia at very high chronic doses; modern reviews (FDA 2003, EFSA 2000) concluded no cancer risk at human exposure levels but the issue is not fully resolved (Mishra 2020 review). Animal evidence suggests gut microbiome disruption (Bian 2017 — male mice on Ace-K showed altered microbiota and metabolic markers). Manufacturing uses methylene chloride, with potential residue concerns. Purely cosmetic additive — risk:benefit unfavorable for supplements.

A flavoring derived from natural sources to taste of grape

Inorganic compound used as an anti-caking and flow agent in powdered supplements

Natural acid derived from citrus fruits

Naturally occurring organic acid found in apples, used as a flavor enhancer and acidulant in supplements