Adults

Potential carcinogen in animal studies; may affect thyroid function; restricted in some countries

IARC classifies cosmetic-grade talc not containing asbestos as Group 2B (possibly carcinogenic to humans); perineal talc use as Group 2A (probably carcinogenic). Johnson & Johnson voluntarily withdrew talc-based baby powder from US/Canada in 2020 and globally in 2022 after extensive litigation tied to ovarian-cancer and mesothelioma cases. The 2018 FDA contamination survey found asbestos in 9 of 52 cosmetic talc products tested. As a supplement excipient talc is a pure manufacturing convenience — no nutritional or functional benefit to the user — so the asbestos-exposure risk has no offsetting upside. Safer alternatives (silicon dioxide, microcrystalline cellulose, rice hulls) are widely available.

Banned in the EU (2022) over concerns that its ultra-fine particles may damage DNA in gut cells. Still allowed in the US. Used only for white coloring — provides no health benefit.

May trigger sensitivity in some individuals; behavioral concerns in susceptible children

Spikes blood sugar faster than table sugar (glycemic index 85–105). Research links it to gut bacteria changes that may promote intestinal inflammation (Nickerson et al. 2015). Used as a cheap filler — adds nothing beneficial.

Vitamin B7, a water-soluble B-vitamin.

Synthetic form of vitamin B9 used for fortification — supports red blood cell formation and neural tube development. Pharmacologically distinct from the natural/active form (5-methyltetrahydrofolate, methylfolate).

An inorganic magnesium salt used as a magnesium source or bulking mineral.