BioStacks
Other Ingredients (7)
Caramel ColorColor
Class III and IV caramel colors contain 4-methylimidazole (4-MEI), classified by IARC as Group 2B (possibly carcinogenic to humans) in 2011 (Monograph Vol. 101). California Prop 65 lists 4-MEI as a known carcinogen; products delivering >29 mcg/day require a cancer warning label. NTP TR-535 (2007) found 4-MEI caused lung tumors in mice. Major cola brands (Coca-Cola, Pepsi) voluntarily reformulated 2012-2014 to reduce 4-MEI below California thresholds. Because labels never specify Class I (sugar + heat only, safer) vs Class III/IV (ammonia-process, contains 4-MEI), consumers cannot verify which they're consuming. Combined with the additive's purely cosmetic purpose, the risk:benefit ratio is unfavorable for any supplement.
Titanium DioxideColorant
Banned in the EU (2022) over concerns that its ultra-fine particles may damage DNA in gut cells. Still allowed in the US. Used only for white coloring — provides no health benefit.
Silicon DioxideAnti-caking
Fine silica powder used to prevent clumping
Calcium StearateLubricant
Calcium salt of stearic acid used as a lubricant and anti-sticking agent
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
GelatinCapsule
Protein derived from collagen, used in traditional capsule shells
HypromelloseCapsule
Plant-derived capsule material from cellulose
How to Take It
Best taken in the morning
Many people prefer B-vitamins earlier in the day; take with food to avoid nausea.
With food
General guidance based on the ingredients, not a substitute for the label or your doctor.
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.