BioStacks
Every active here is dosed below the amount studied to work. See how each one compares in the breakdown below.
Ingredients (2)
L-Glutathione Reduced
20%Dose
50 mg
Target
250–1000 mg
Form
Budget
Vitamin C
3%Dose
2.5 mg
Target
100–500 mg
Form
Budget
Other Ingredients (8)
Polysorbate 80Emulsifier
Chassaing et al. 2015 (Nature, PMID 25731162) tested polysorbate 80 directly and showed it thinned the gut mucus barrier, altered microbiota composition, and induced low-grade inflammation and metabolic syndrome in mice. The strongest human evidence is for a related emulsifier rather than polysorbate 80 itself: Chassaing 2022 (Gastroenterology, PMID 34774538) was a controlled human feeding RCT of carboxymethylcellulose (CMC) that found microbial encroachment into the mucus layer — polysorbate 80 has not been tested in an equivalent human trial. In vitro work (e.g. Roberts 2010) shows polysorbate 80 enhances bacterial translocation across intestinal epithelium, and observational data link overall dietary-emulsifier exposure to IBD risk. EFSA is mid re-evaluation of polysorbates (E432–E436). For a supplement excipient with purely cosmetic function (improving the look/texture of soft gels and liquids), the gut-barrier risk profile is unfavorable when safer alternatives (sunflower lecithin, MCT carriers, gum acacia) are widely available.
Sodium BenzoatePreservative
Benzene can form in presence of ascorbic acid plus metals/heat/light; may trigger reactions in sensitive individuals
Natural FlavorsFlavor
Broad regulatory category of flavor constituents derived from natural sources. Composition is proprietary and not disclosed — 'Natural Flavors' can include several hundred different compounds depending on the target flavor profile, including hexane-extracted constituents and proprietary carrier solvents. 'Natural' is a regulatory definition (21 CFR §101.22), not a safety guarantee.
Potassium SorbatePreservative
Natural preservative derived from sorbic acid
Purified WaterSolvent
Water meeting USP specifications used as solvent/vehicle in gummies and liquids
Stevia ExtractSweetener
Zero-calorie natural sweetener extracted from the leaves of Stevia rebaudiana
Sunflower LecithinEmulsifier
Non-GMO, non-allergenic emulsifier derived from sunflower seeds
Sunflower Seed OilCarrier
Common vegetable oil from sunflower seeds used as a carrier in softgels for fat-soluble nutrients
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.