BioStacks
Doctor's Best

5-HTP 100 mg

1 Capsule · 60 servings · $0.22/serving

iHerbAmazon

Best for

Sleep

Ingredients (1)

5-HTP

100%

Dose

100 mg

Target

100–300 mg

Form

—

Other Ingredients (3)

Silicon DioxideAnti-caking

Fine silica powder used to prevent clumping

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

How to Take It

Best taken in the evening

Take in the evening. Amino acids compete for the same transport into the brain, so a protein-heavy meal blunts it.

On an empty stomach
Keep it away from protein-heavy meals
Space it a couple of hours from SAMe

On the label

Adult use: Take 1 capsule daily, with or without food, or as recommended by your nutritionally-informed physician.

Do not combine with St. John's Wort

Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.

General guidance based on the ingredients, not a substitute for the label or your doctor.

Price Check

$13.15

$10$20$50

Cheaper than 80% of 61 5-HTP supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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