Best for
Ingredients (3)
Glycerophosphocholine
100%Dose
300 mg
Target
300–1200 mg
Form
—
Phosphatidylserine
33%Dose
100 mg
Target
300–800 mg
Form
—
Calcium
97 mgTrace amount — not scored
Other Ingredients (5)
TalcAnti-caking
IARC classifies cosmetic-grade talc not containing asbestos as Group 2B (possibly carcinogenic to humans); perineal talc use as Group 2A (probably carcinogenic). Johnson & Johnson voluntarily withdrew talc-based baby powder from US/Canada in 2020 and globally in 2022 after extensive litigation tied to ovarian-cancer and mesothelioma cases. The 2018 FDA contamination survey found asbestos in 9 of 52 cosmetic talc products tested. As a supplement excipient talc is a pure manufacturing convenience — no nutritional or functional benefit to the user — so the asbestos-exposure risk has no offsetting upside. Safer alternatives (silicon dioxide, microcrystalline cellulose, rice hulls) are widely available.
Magnesium StearateLubricant
A salt of stearic acid used as a lubricant in tablet and capsule production
Silicon DioxideAnti-caking
Fine silica powder used to prevent clumping
Dicalcium PhosphateBinder
Calcium and phosphorus compound used as binder
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
How to Take It
Best taken in the evening
Evening use targets nighttime cortisol; fat-soluble, so take with food.
On the label
Take 1 capsule twice per day between meals, not later than 4 pm. Intakes up to 6 capsules per day may be beneficial, as recommended by a nutritionally informed physician. Store in a cool dry place.
The label says to take it on an empty stomach. What's in this one sits better with food, and you give up little by taking it that way.
General guidance based on the ingredients, not a substitute for the label or your doctor.
Price Check
$20.21
Cheaper than 71% of 12 alpha-GPC supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.