BioStacks
Ingredients (2)
Pine Bark Extract
100%Dose/day
200 mg
Target
50–200 mg
Form
—
Oligomeric Proanthocyanidins
80%Dose/day
120 mg
Target
150–300 mg
Form
—
Other Ingredients (10)
Agave NectarSweetener
Agave nectar is ~70–90% fructose by composition (vs sucrose's 50% and high-fructose corn syrup's 55%). Low glycemic index is a fructose artifact — fructose bypasses insulin-mediated metabolism and is preferentially shuttled to hepatic de novo lipogenesis. Chronic high-fructose intake is associated with hepatic steatosis, insulin resistance, and adverse lipid changes (Stanhope 2009 RCT). The 'natural' / 'healthier than sugar' marketing positioning contradicts the metabolic profile. Per brand voice: this is a clearer case than most of marketing-vs-science divergence.
Agave NectarSweetener
Agave nectar is ~70–90% fructose by composition (vs sucrose's 50% and high-fructose corn syrup's 55%). Low glycemic index is a fructose artifact — fructose bypasses insulin-mediated metabolism and is preferentially shuttled to hepatic de novo lipogenesis. Chronic high-fructose intake is associated with hepatic steatosis, insulin resistance, and adverse lipid changes (Stanhope 2009 RCT). The 'natural' / 'healthier than sugar' marketing positioning contradicts the metabolic profile. Per brand voice: this is a clearer case than most of marketing-vs-science divergence.
Rice FlourFiller
Rice-based ingredients carry risk of inorganic arsenic contamination (FDA and Consumer Reports). Rice accumulates arsenic from soil at higher rates than other grains. Used as a cheap filler — adds nothing beneficial.
Rice ExtractFiller
Rice-based ingredients carry risk of inorganic arsenic contamination. Vague labeling — 'rice extract' does not specify what is extracted or standardized. Used as a cheap filler with no supplemental benefit.
Tapioca DextrinCarrier
A starch hydrolysate from tapioca used as a carrier and flow agent
Guar GumThickener
Natural thickener derived from guar beans
Gum AcaciaBinder
Natural plant gum (acacia) used as a binder, stabilizer, and emulsifier in foods and supplements
Vegetable OilCarrier
Edible oils used as carriers in softgels and as processing aids
How to Take It
Take it anytime
Timing doesn't matter for this one — taking it consistently does.
With or without food
Split into 2 doses across the day
On the label
Adults, as a dietary supplement, take one (1) tablet, twice daily.
General guidance based on the ingredients, not a substitute for the label or your doctor.
Price Check
$39.97
Near the median of 35 pycnogenol supplements
Track this supplement in your stack
Get personalized insights, interactions, and coverage recommendations.
Get Started FreeSimilar Supplements
Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.