BioStacks
Best for
Ingredients (1)
L-5-Hydroxytryptophan
50%Dose
50 mg
Target
100–300 mg
Form
—
Other Ingredients (2)
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
HypromelloseCapsule
Plant-derived capsule material from cellulose
How to Take It
Best taken in the evening
Take in the evening. Amino acids compete for the same transport into the brain, so a protein-heavy meal blunts it.
On an empty stomach
Keep it away from protein-heavy meals
Space it a couple of hours from SAMe
On the label
Take 1 capsule one to three times daily before meals, or as recommended by your healthcare professional.
Do not combine with St. John's Wort
Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.
General guidance based on the ingredients, not a substitute for the label or your doctor.
Price Check
$23.50
Near the median of 61 5-HTP supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.