Each serving delivers 1g of **Glycine**, but the clinical research on sleep quality used 3g before bedtime — so you'd need to take three capsules to reach the studied dose. At that intake, you're right at the effective minimum for supporting sleep onset and reducing next-day fatigue.

Glycine also serves as a building block for collagen and plays a role in creatine synthesis, giving you potential relevance for skin and muscle support beyond sleep. The capsule form makes dosing flexible, which helps since individual needs vary.

The main tradeoff is pill burden. Getting to the 3g clinical dose means you're taking three capsules per night, which makes a powder format more practical at this dose level.

BioStacks
Life Extension

Glycine 1000 mg

1 Capsule · 100 servings · $0.12/serving

iHerbAmazon

Every active here is dosed below the amount studied to work. See how each one compares in the breakdown below.

Best for

Sleep

Ingredients (1)

Glycine

33%

Dose

1 g

Target

3–5 g

Form

—

Other Ingredients (2)

Ascorbyl PalmitateAntioxidant

Fat-soluble form of vitamin C used as preservative

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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