BioStacks
Best for
Ingredients (1)
St. John's Wort extract
50%Dose
300 mg
Target
600–1200 mg
Form
Not listed
Other Ingredients (3)
Rice FlourFiller
Rice-based ingredients carry risk of inorganic arsenic contamination (FDA and Consumer Reports). Rice accumulates arsenic from soil at higher rates than other grains. Used as a cheap filler — adds nothing beneficial.
Ascorbyl PalmitateAntioxidant
Fat-soluble form of vitamin C used as preservative
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
How to Take It
Best taken in the morning
Take earlier in the day with food. Check the conflicts below — it interacts seriously with serotonergic compounds.
With food
On the label
Take one (1) capsule one or twice daily on an empty stomach, or as recommended by a healthcare practitioner.
The label says to take it on an empty stomach. What's in this one sits better with food, and you give up little by taking it that way.
Do not combine with 5-HTP, SAMe or Tryptophan
Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.
General guidance based on the ingredients, not a substitute for the label or your doctor.
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.