Every active here is dosed below the amount studied to work. See how each one compares in the breakdown below.
Best for
Ingredients (3)
SAMe
25%Dose
200 mg
Target
800–1600 mg
Form
Standard
Calcium
20 mgTrace amount — not scored
Magnesium
10 mgTrace amount — not scored
Other Ingredients (3)
Gellan GumGelling Agent
Microbial polysaccharide produced by Sphingomonas elodea, used as a gelling and stabilizing agent
LeucineFlow Aid
Branched-chain amino acid used as a processing aid
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
How to Take It
Best taken in the morning
Take in the morning on an empty stomach — it can be activating and may disturb sleep later in the day.
On the label
One to two (1-2) capsules daily, between meals, or as directed by a healthcare professional.
Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.
General guidance based on the ingredients, not a substitute for the label or your doctor.
Price Check
$62.10
Pricier than 89% of 638 calcium supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.