Best for
Ingredients (3)
Glucosamine Hydrochloride
100%Dose/day
1500 mg
Target
1000–1500 mg
Form
Premium
Chondroitin Sulfate
100%Dose/day
1200 mg
Target
800–1200 mg
Form
Standard
Methylsulfonylmethane
25%Dose/day
249 mg
Target
1000–3000 mg
Form
—
Calories, macros & sodium.
Other Ingredients (8)
CarboxymethylcelluloseThickener
Carboxymethylcellulose was the second emulsifier (with polysorbate 80) in Chassaing et al. 2015 (Nature, PMID 25731162), which showed mucus-barrier thinning, a microbiota shift toward pro-inflammatory species, low-grade inflammation, and metabolic syndrome in mice. Chassaing 2022 (Gastroenterology, PMID 34774538) tested CMC directly in a randomized controlled human feeding trial and found reduced microbial diversity and bacterial encroachment into the normally sterile mucus layer in a susceptible subset of participants. EFSA's 2018 re-evaluation could not establish a safe level due to data gaps. For a purely textural excipient, the gut-barrier risk profile is unfavorable when safer thickeners are widely available.
Magnesium StearateLubricant
A salt of stearic acid used as a lubricant in tablet and capsule production
Silicon DioxideAnti-caking
Fine silica powder used to prevent clumping
CrospovidoneDisintegrant
Cross-linked synthetic polymer used as a tablet disintegrant to help tablets break apart quickly in the stomach
GlycerinHumectant
Sweet-tasting liquid used in soft capsules and liquids
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
Microcrystalline CelluloseBinder
Plant-derived cellulose used as a binder and filler in supplements
Stearic AcidLubricant
Saturated fatty acid used as tablet lubricant
How to Take It
Take it anytime
Take with food to avoid stomach upset. Benefits, where they exist, take weeks of daily use to appear.
On the label
Take 1 tablet, three times daily, with a meal.
General guidance based on the ingredients, not a substitute for the label or your doctor.
Price Check
$11.49
Cheaper than 97% of 65 chondroitin supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.