Vitamin C + Zinc (Natural Citrus)

Dose context matters. As a trace excipient in a tablet coating or capsule, the amount is minimal and not a meaningful concern. The evidence below applies to the gram-level intakes typical of sweetened protein powders, pre-workouts, and drink mixes: a 2022 human trial (Suez et al., Cell) showed sucralose disrupts gut bacteria and worsens blood sugar control in healthy adults, and a 2023 study (Schiffman et al.) found that sucralose-6-acetate — a compound formed when sucralose is digested — was genotoxic to human cells in vitro. It remains an artificial sweetener with no nutritional purpose.

A FODMAP sugar alcohol that can cause GI distress (bloating, gas, diarrhea) at higher doses. Supplement amounts are typically small, but individuals with IBS or sugar alcohol sensitivity may react even at low doses.

Natural yellow-orange colorant derived from the seeds of the achiote tree (Bixa orellana)

A simple glucose sugar used as a bulking agent, sweetener, and tablet diluent

Fine silica powder used to prevent clumping

A salt of stearic acid used as a lubricant in tablet and capsule production

Cross-linked synthetic polymer used as a tablet disintegrant to help tablets break apart quickly in the stomach

Plant-derived cellulose used as a binder and filler in supplements