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What it does
L-5-Hydroxytryptophan
Form not confirmedGrade —
Studied for low mood, but reliable evidence of benefit remains insufficient.
Ingredients (1)
Other ingredients
No other ingredients listed
Lab testing
How to take it
On an empty stomach
Keep it away from protein-heavy meals
Space it a couple of hours from SAMe
Do not combine with St. John's Wort
Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.
Price check
$46.99
$0.52 / serving
Pricier than 90% of 61 5-HTP supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.
Not medical advice. Consult your healthcare professional.