BioStacks
Patient One MediNutritionals

Saffro-Calm Plus

Liquid · 4 Sprays (0.66 M L) · 45 servings · $0.58/serving

iHerbAmazon

Best for

Stress & Mood

Ingredients (2)

Affron

100%

Dose

28 mg

Target

14–30 mg

Form

—

Echinacea angustifolia root extract

10%

Dose

30 mg

Target

300–1500 mg

Form

—

Other Ingredients (4)

Natural FlavorsFlavor

Broad regulatory category of flavor constituents derived from natural sources. Composition is proprietary and not disclosed — 'Natural Flavors' can include several hundred different compounds depending on the target flavor profile, including hexane-extracted constituents and proprietary carrier solvents. 'Natural' is a regulatory definition (21 CFR §101.22), not a safety guarantee.

Wildflower HoneySweetener

A natural sweetener and humectant produced by bees, used in syrups and lozenges

Citric AcidAcidulant

Natural acid derived from citrus fruits

Purified WaterSolvent

Water meeting USP specifications used as solvent/vehicle in gummies and liquids

How to Take It

Take it anytime

Trials dose it once or twice daily for 6-8 weeks; timing within the day wasn't a variable. Consistency is what matters.

With or without food

On the label

Take 4 sprays daily.

General guidance based on the ingredients, not a substitute for the label or your doctor.

Price Check

$26.00

$10$20

Pricier than 75% of 21 saffron supplements

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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