BioStacks
Best for
Ingredients (1)
5-HTP
100%Dose
100 mg
Target
100–300 mg
Form
—
Other Ingredients (2)
Hypoallergenic Plant FiberFiller
Plant-derived cellulose fiber used as a hypoallergenic filler, common in Thorne and Pure Encapsulations products
Capsule ShellCapsule
Generic capsule shell where the label does not specify the material. Common materials are hypromellose (HPMC) for vegetarian capsules and gelatin for traditional capsules — both are GRAS-listed and safe. Fish gelatin and pullulan variants also exist.
How to Take It
Best taken in the evening
Take in the evening. Amino acids compete for the same transport into the brain, so a protein-heavy meal blunts it.
On an empty stomach
Keep it away from protein-heavy meals
Space it a couple of hours from SAMe
On the label
As a dietary supplement, take 1 capsule, 1-3 times daily, before meals.
Do not combine with St. John's Wort
Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.
General guidance based on the ingredients, not a substitute for the label or your doctor.
Price Check
$58.80
Pricier than 96% of 61 5-HTP supplements
Track this supplement in your stack
Get personalized insights, interactions, and coverage recommendations.
Get Started FreeSimilar Supplements
Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.