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What it does
5-HTP
Form not confirmedGrade —
Studied for low mood, but reliable evidence of benefit remains insufficient.
Ingredients (1)
Other ingredients
Hypoallergenic Plant FiberFiller
Plant-derived cellulose fiber used as a hypoallergenic filler, common in Thorne and Pure Encapsulations products
Capsule ShellCapsule
Generic capsule shell where the label does not specify the material. Common materials are hypromellose (HPMC) for vegetarian capsules and gelatin for traditional capsules — both are GRAS-listed and safe. Fish gelatin and pullulan variants also exist.
Lab testing
How to take it
On an empty stomach
Keep it away from protein-heavy meals
Space it a couple of hours from SAMe
On the label
As a dietary supplement, take 1 capsule, 1-4 times daily, before meals, or as directed by a health professional.
Do not combine with St. John's Wort
Each of these raises serotonin activity on top of St. John's Wort, and together they can trigger serotonin syndrome — agitation, rapid heartbeat, raised blood pressure. Not without medical supervision.
Price check
$101.40
$0.56 / serving
Pricier than 99% of 61 5-HTP supplements
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Sources & Scoring
Nutrient data (RDA, UL, and safety thresholds) sourced from the NIH Office of Dietary Supplements and the National Academies Dietary Reference Intakes (DRI).
This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.
The score analyzes what's on the label: ingredient doses vs. studied ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.
Not medical advice. Consult your healthcare professional.