BioStacks
Source Naturals

B-6 50 mg

1 Tablet · 100 servings

iHerbAmazon
63 / 100Good

Best for

Energy

Score Breakdown

Formulation
84
Safety
75
Final score
63/100

Ingredients (2)

Vitamin B6

100%

Dose

50 mg

Target

25–100 mg

Form

Premium

Calcium

28 mg

Trace amount — not scored

Other Ingredients (5)

CarboxymethylcelluloseThickener

Carboxymethylcellulose was the second emulsifier (with polysorbate 80) in Chassaing et al. 2015 (Nature, PMID 25731162), which showed mucus-barrier thinning, a microbiota shift toward pro-inflammatory species, low-grade inflammation, and metabolic syndrome in mice. Chassaing 2022 (Gastroenterology, PMID 34774538) tested CMC directly in a randomized controlled human feeding trial and found reduced microbial diversity and bacterial encroachment into the normally sterile mucus layer in a susceptible subset of participants. EFSA's 2018 re-evaluation could not establish a safe level due to data gaps. For a purely textural excipient, the gut-barrier risk profile is unfavorable when safer thickeners are widely available.

Magnesium StearateLubricant

A salt of stearic acid used as a lubricant in tablet and capsule production

Calcium CarbonateBuffer

Common calcium salt used as a buffering agent, filler, or mineral fortification in supplements

Microcrystalline CelluloseBinder

Plant-derived cellulose used as a binder and filler in supplements

Stearic AcidLubricant

Saturated fatty acid used as tablet lubricant

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Sources & Scoring

Nutrient data (RDA, UL, and safety thresholds) sourced from: NIH Office of Dietary Supplements and National Academies Dietary Reference Intakes (DRI).

This is not medical advice. Consult a healthcare provider before making changes to your supplement routine.

The score analyzes what's on the label: ingredient doses vs. clinical ranges, chemical forms, evidence levels, and known interactions. It does not verify label accuracy or test for contaminants — for that, look for third-party certifications like USP or NSF.

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